Eosinophil infiltration into head and neck squamous cell carcinoma.
Eosinophils are a type of immune cell that can be present in large numbers in head and neck cancer. The role that eosinophils play in the tumour still isn’t clear, but some evidence suggests that they may be beneficial for patients. This study will determine the function of these cells in head and neck cancer. It will also test strategies for altering tumour eosinophils in cancer models. This study will provide preclinical evidence for whether targeting eosinophils in head and neck cancer could be a useful strategy to improve patient survival.