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Academic Surgeon-Scientist Research Scholarship (ASSRS) - 2025

Sensory Gating Dysfunction and Tinnitus: Pathophysiology and Therapeutic Modulation with rTMS
Dr. Nayellin Reyes-Chicuellar

Project Description

Dr. Nayellin Reyes-Chicuellar’s research investigates the complex brain mechanisms behind tinnitus, a condition that profoundly impacts millions globally. This project focuses on sensory gating, a neural process that filters irrelevant auditory information. In tinnitus sufferers, this process becomes disrupted, leading to the persistent perception of phantom sounds.

The study aims to understand the role of key brain regions, including the thalamus, auditory cortex, and prefrontal cortex, in sensory gating dysfunction. By measuring brain responses and neural activity, Dr. Reyes-Chicuellar will identify how these circuits are altered in tinnitus and explore potential interventions.

A key component of the project is the application of repetitive Transcranial Magnetic Stimulation (rTMS), a cutting-edge, non-invasive technique that targets specific brain areas to modulate neural activity. The research evaluates how rTMS can restore sensory gating functionality and alleviate tinnitus symptoms.

This innovative approach has the potential to redefine treatment strategies for tinnitus, offering new hope to patients while advancing the scientific understanding of this complex condition. Supported by the Garnett Passe and Rodney Williams Academic Surgeon-Scientist Research Scholarship, this project is at the forefront of otolaryngology research.

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